Additional Info: |
Atypical polypoid adenomyoma (APA) of the uterus is a rare tumor composed of atypical glands surounded by smooth muscle. Squamous metaplasia can occur. As seen in this image, distinguishing this lesion from true invasive adenocarcinoma can be a REAL challenge. Most APAs do not invade the myometrium, but rather have pushing margins. The glands are not surrounded by desmoplastic stroma but rather by smooth muscle. There are no overtly malignant glands in an APA. Typically these tumors occur in women of reproductive age. These tumors are considered benign. |